A combination of guaifenesin and dextromethorphan, it is widely available under the brand name Robitussin and the generic Tussin.

This article discusses Robitussin DM cough syrup, its uses, and potential side effects. It also includes dosing information and warnings.

Common Uses

The ingredients in this medicine help to loosen mucus and suppress coughing. People commonly take this medicine for coughs associated with colds, allergies, the flu, and other respiratory illnesses.

It should not be used in children under 6 without talking to the child’s doctor first. 

Dosing

Adults 12 and older: Two teaspoons every four hours as needed for cough. Do not take more than six doses in 24 hours. Children ages 6 to 12: One teaspoon every four hours. Do not take more than six doses in 24 hours.

Side Effects

Every medication has the potential to cause side effects. Most are minor and the benefits outweigh the risks.

Drowsiness or dizzinessHives or skin rashNausea, stomach pain or vomiting

Rare but serious side effects that should be reported to your healthcare provider immediately:

ConfusionExcitement, nervousness or restlessnessSevere nausea and vomitingSlurred speechSeizures or convulsions - in childrenShakey movements - in childrenSlow or troubled breathing - in children

Warnings

Do not use this medication if you are taking an MAOI (medication for depression, psychiatric, emotional conditions or Parkinson’s disease) or for two weeks after stopping an MAOI.

Ask a healthcare provider before using this medicine if you have a chronic cough that is caused by asthma, smoking, or emphysema.

Talk to your healthcare provider prior to taking this medicine if you are pregnant or breastfeeding as well.

Stop use and ask a healthcare provider if:

Pain or cough worsens or lasts more than seven daysCough occurs with fever, headache, or rash that won’t go away

Do not give Robitussin or other cough suppressants to children under 6.

Signs of an overdose include breathing problems, blue-tinged fingernails and lips, increased body temperature, drowsiness, an unsteady gait, and muscle twitches. If you suspect someone has taken too much DXM, call poison control at 1-800-222-1222 or seek immediate medical treatments. 

If you have a chronic cough that is caused by asthma, smoking, or emphysema, talk to your healthcare provider before taking Robitussin DM.

Another formulation, Robitussin Nighttime DM, may make you sleepy. It contains the antihistamine doxylamine succinate instead of guaifenesin, which can cause drowsiness.